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. 2018 Apr 5;13(4):e0195528. doi: 10.1371/journal.pone.0195528

Fig 6. Dexamethasone suppressed pathological molecular remodeling induced in the RV as well as the LV.

Fig 6

(A) mRNA expression of IL1b and IL6, normalized to GAPDH. Dexamethasone inhibited overexpression of IL1b in both RV and LV myocardium induced by transverse aortic constriction (TAC) for 2 days. (B) mRNA expression of RCAN1 and BNP normalized to GAPDH. Dexamethasone suppressed up-regulation of RCAN1 and BNP in RV and LV myocardium induced by two-day TAC. Results are expressed as mean ± s.e.m. (n = 5). TAC 2d Veh, TAC for 2 days with vehicle treatment; TAC 2d DXM, TAC for 2 days with dexamethasone treatment. n.s. *, p<0.05 versus sham group; ✝, p<0.05 versus the TAC 2d Veh group.