Figure 4. Distribution of lineage-biased HSCs in the mouse BM after NG2+ cells depletion.
Localization of phenotypic Lineage− CD48− CD150+ vWF-eGFP− (A, C) and vWF-eGFP+ (B, D) HSCs in the mouse BM relative to MK (A, B) and arterioles (C, D) in control (iDTR;Vwf-eGFP) and NG2-creERTM;iDTR;Vwf-eGFP mice, 16 days after DT treatment. n = 172 vWF− and n = 32 vWF+ HSCs from control iDTR;Vwf-eGFP; n = 163 vWF− and n = 26 vWF+ HSCs from NG2-creERTM;iDTR;Vwf-eGFP. P values were determined by two-sample KS test. Error bars S.E.M.