Table 1.

Curated gene lists from MSigDB significantly overlapping with the list of SSRP1-enriched genes (only lists with p<0.00E-6 are shown) organized in functional categories. See also Tables S1–S4.

Functional category	Gene Set Name	p-value
MYC-related	DANG BOUND BY MYC	0.00E+00
	DANG MYC TARGETS UP	0.00E+00
	BENPORATH MYC TARGETS WITH EBOX	5.58E-14
	BENPORATH MYC MAX TARGETS	1.96E-12
	GGGAGGRR V$MAZ Q6	8.47E-09
	LEI MYB TARGETS	9.08E-09
Stress-induced	ENK UV RESPONSE KERATINOCYTE UP	0.00E+00
	DAZARD RESPONSE TO UV NHEK UP	1.11E-16
	KRIEG HYPOXIA NOT VIA KNOCKDOWNM3A	1.75E-10
	HU GENOTOXIC DAMAGE 24HR	2.56E-09
	WINTER HYPOXIA METAGENE	7.04E-09
	HARRIS HYPOXIA	1.41E-08
	PHONG TNF TARGETS UP	2.05E-08
	DAZARD UV RESPONSE CLUSTER G2	2.25E-08
Cancer-related	WANG TUMOR INVASIVENESS UP	0.00E+00
	GRADE COLON CANCER UP	1.11E-16
	OSMAN BLADDER CANCER DN	3.89E-15
	CHNG MULTIPLE MYELOMA HYPERPLOID UP	6.55E-15
	LI AMPLIFIED IN LUNG CANCER	7.78E-11
	ZUCCHI METASTASIS DN	7.31E-10
	NUTT GBM VS AO GLIOMA DN	9.06E-10
	SWEET LUNG CANCER KRAS UP	2.82E-09
	ACEVEDO LIVER CANCER DN	3.51E-09
	DIAZ CHRONIC MEYLOGENOUS LEUKEMIA DN	4.35E-08
Meiosis	REACTOME MEIOSIS	0.00E+00
	REACTOME MEIOTIC RECOMBINATION	0.00E+00
	REACTOME MEIOTIC SYNAPSIS	3.15E-14
Ribosome	KEGG RIBOSOME	0.00E+00
	MIPS RIBOSOME CYTOPLASMIC	0.00E+00
	MIPS 60S RIBOSOMAL SUBUNIT CYTOPLASMIC	0.00E+00
	MIPS 40S RIBOSOMAL SUBUNIT CYTOPLASMIC	2.22E-16
Stimulated by growth factors	NAGASHIMA EGF SIGNALING UP	8.58E-13
	AMIT EGF RESPONSE 40 HELA	1.58E-11
	NAGASHIMA NRG1 SIGNALING UP	6.56E-11
	PEDERSEN METASTASIS BY ERBB2 ISOFORM 1	1.12E-09
Chromatin organization	REACTOME DEPOSITION OF NEW CENPA CONTAINING	1.11E-16
	NUCLEOSOMES AT THE CENTROMERE	3.33E-12
	REACTOME CHROMOSOME MAINTENANCE
Differentiation	BENPORATH SOX2 TARGETS	4.74E-09
	ESC V6.5 UP EARLY.V1 DN	7.69E-07
	ESC J1 UP EARLY.V1 DN	9.86E-06