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A cluster of gene products in the weak stream model. Underscored nodes are the proteins that have been shown to be relevant to lower urinary tract syndrome in the systematic literature search (Table E2; available online at www.redjournal.org). Green, red, and gray connections indicate activation, inhibition, and unspecified, respectively. Abbreviations: EGFR = epidermal growth factor receptor; PKC protein kinase C. (A color version of this figure is available at www.redjournal.org.)
