TABLE 3.

Probabilistic bias analysis accounting for unmeasured confounding by current smoking and sarcoidosis misclassification

	Hazard ratio (95% CI)
Conventional analysis
Random error	1.61 (1.47–1.76)
Sensitivity analyses#
Unmeasured confounding by current smoking
Systematic error	1.74 (1.71–1.78)
Systematic error and random error	1.74 (1.60–1.93)
Misclassification of sarcoidosis definition
Systematic error	1.54 (1.42–1.66)
Systematic error and random error	1.54 (1.31–1.79)
Unmeasured confounding by current smoking and
misclassification of sarcoidosis definition
Systematic error	1.66 (1.52–1.78)
Systematic error and random error	1.66 (1.40–1.93)

^#: estimated by simulations based on predetermined assumptions for bias parameters (see online supplementary material for their specification). Confidence intervals are simulation intervals for systematic error analyses and bootstrapped intervals for systematic error and random error analyses.