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. 2014 May 5;2014(5):CD003968. doi: 10.1002/14651858.CD003968.pub4
Methods RCT. 3 arms. Assessed at pre‐treatment, post‐treatment
Participants End of treatment n = 43
Start of treatment n = 51
Sex: 34 F, 17 M
Mean age = 12.9
Source = referred by physicians to children's hospital
Diagnosis = migraine
Mean years of pain = not given: most over 2 years
Interventions "Relaxation training" "Cognitive coping" "Attention control"
Outcomes Primary pain outcome: headache diary
Primary disability outcome: none
Primary depression outcome: Child Depression Rating Scale
Primary anxiety outcome: State Trait Anxiety Inventory
1. Headache index (intensity, frequency, duration, medication taken: diary)
2. State Trait Anxiety Inventory (STAI) or State‐Trait Anxiety Inventory for Children (STAI‐C)
3. Children's Depression Rating Scale
Notes Original study
Total quality = 20/35
Treatment quality = 6/9
Design quality = 14/26
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "... and randomly assigned to treatment" Comment: probably done, no method described
Allocation concealment (selection bias) Unclear risk No description found in text Comment: probably not done
Blinding of outcome assessment (detection bias) All outcomes Unclear risk No description found in text
Comment: probably not done
Incomplete outcome data (attrition bias) All outcomes Low risk "Over the course of treatment there were 8 drop‐outs. A chi‐square analysis comparing attrition rates across interventions was not significant." Comment: attrition adequately reported and no significant differences between completers and non‐completers reported
Selective reporting (reporting bias) High risk Data were incompletely reported