Fig. 3.

Pre-ranked GSEA of CIN3 or Cancer ‘UP’ and ‘DOWN’ gene signatures in K14E7 versus C57Bl/6. Ranking of genes in the ‘UP’ gene signatures or ‘DOWN’ gene signatures in the K14E7 ranked list are shown at the bottom of each pre-ranked GSEA plot. Position and frequency of genes contributing the most to each enrichment are highlighted in teal for genes in CIN3 signatures or purple for genes in Cancer signatures. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)