Fig. 4.

Heat map of relative gene expression of genes that contribute the most to the enrichment of K14E7 ‘UP’ gene set in CIN3 versus CIN1/CIN2. Relative gene expression in K14E7 mice and C57BL/6 mice are provided in the right panel. The colour scheme for both heat maps correspond to the relative expression level normalised to a range from 0 to 1 using the minimum and maximum values within each row/gene and represented as a colour gradient from blue to red. Sample groups for each are additionally provided with coloured annotations. Gene symbols that correspond to cell cycle-related genes are annotated in pink and gene symbols that correspond to immune-related genes are annotated in green. Uncategorised gene symbols are in black. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)