Fig. 6.

Gene set testing of K14E7 on C57BL/6 14DPG and 28DPG ‘UP’ and ‘DOWN’ gene signatures in human CIN3 versus CIN1/CIN2 and cervical cancer versus CIN3. (A-B) GSEA analysis of (A) CIN3 versus CIN1/CIN2 or (B) cancer versus CIN3 of K14E7 on C57BL/6 14DPG and 28DPG ‘UP’ or ‘DOWN’ signatures. Ranking of genes in the ‘UP’ gene signatures or ‘DOWN’ gene signatures are shown at the bottom of each GSEA plot. Position and frequency of genes contributing the most to each enrichment are highlighted (14DPG, pink; 28DPG, blue). (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)