Table 4.
The effect of exercise on APRT, HPRT and PRPP-S activities and PRPP concentration in RBCs
| Sedentary group | Trained group | |||||
|---|---|---|---|---|---|---|
| Rest | Post-exercise | 30-min recovery | Rest | Post-exercise | 30-min recovery | |
| APRT (nmol/mgHb/min) | 0.39 (0.35–0.43) | 0.39 (0.38–0.42) | 0.37 (0.33–0.42) | 0.48 (0.48–0.57)** | 0.44 (0.42–0.49)** | 0.45 (0.42–0.52)** |
| HGPRT (nmol/mgHb/min) | 1.68 (1.55–1.88) | 1.77 (1.61–1.88) | 1.68 (1.53–1.82) | 1.91 (1.86–2.03)** | 1.84 (1.85–1.93)** | 1.87 (1.84–1.92)** |
| PRPP–S (nmol/mgHb/min) | 1.23 (1.19–1.25) | 1.23 (1.20–1.24) | 1.19 (1.17–1.22) | 1.32 (1.29–1.35)** | 1.30 (1.22–1.35)** | 1.31 (1.27–1.35)** |
| PRPP (µmol/L) | 5.6 (4.90–5.90) | 5.2 (5.24–6.70) | 4.9 (4.86–5.52) | 7.1 (6.52–7.85)* | 7.0 (5.82–7.33)* | 7.1 (6.91–7.4)* |
Values are given as median (Q 25–Q 75)
APRT adenine phosphoribosyltransferase (EC 2.4.2.7), HGPRT hypoxanthine-guanine phosphoribosyltransferase (HGPRT; EC 2.4.2.8), PRPP-S 5-phosphoribosyl-1-pyrophosphate synthetase (EC 2.7.6.1), PRPP 5-phosphoribosyl-1-pyrophosphate
* P < 0.01; ** P < 0.001; different from sedentary subjects