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. 2018 Feb 21;208(4):1513–1522. doi: 10.1534/genetics.118.300791

Figure 1.

Figure 1

Tarbp2 −/−;Prkra −/− mutants die at midgestation. (A) An image summarizing the developmental stages of survival or embryonic lethality of Dicer −/−, Tarbp2 −/−, or Prkra −/− single mutants and Tarbp2 −/−; Prkra −/− double mutants. (B) Number of embryonic day (E)12.5 embryos harvested from crossing Tarbp2 −/+; Prkra −/+ double heterozygotes. χ2 = 19.283 (8 d.f.), two-tailed P-value = 0.0134. (C) An E18.5 Tarbp2 −/−;Prkra −/− mutant that is significantly smaller than a Tarbp2 +/−;Prkra +/+ sibling, and has a shorter snout.