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. 2018 Feb 21;208(4):1513–1522. doi: 10.1534/genetics.118.300791

Figure 2.

Figure 2

Tarbp2 regulates processing of a subclass of pre-miRNAs (microRNAs). (A) Plot of miRNA transcripts in Tarbp2 −/− whole embryos at embryonic day (E)15.5 and their fold-changes by average expression using RNA-sequencing (RNA-seq). (B) Plot of miRNA transcripts in Prkra −/− whole embryos at E15.5 and their fold-changes by average expression using RNA-seq. (C) Plot of overall expression fold-change of 3p and 5p miRNA transcripts in C57Bl6 Tarbp2 −/− whole embryos at E15.5 compared to wild-type embryos. (D) Plot of 3p arm miRNA transcripts with one, two, or three nucleotide (n = 1, 2, or 3) addition (An) or deletion (Dn) at the 5′ end in Tarbp2 −/− whole embryos at E15.5 and their fold-changes by counts per million (cpm) using RNA-seq.