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. 2018 Feb 21;208(4):1513–1522. doi: 10.1534/genetics.118.300791

Figure 3.

Figure 3

Prkra is not required for canonical microRNA (miRNA) biogenesis at embryonic day (E)15.5: (A) Fold-change of overall expression of 3p and 5p miRNA transcripts in C57Bl6 Prkra −/− whole embryos at E15.5 compared to wild-type embryos. (B) Plot of 3p arm miRNA transcripts with one, two, or three nucleotide (n = 1, 2, or 3) addition (An) or deletion (Dn) at the 5′ end in Prkra −/− whole embryos at E15.5 and their fold-changes by counts per million (cpm) using RNA-sequencing. (C) A table chart summarizing the type of deregulation and number of miRNAs in Tarbp2 −/− and Prkra −/− compared to wild-type. (D) Chart of percent reads of miRNAs vs. other small noncoding RNAs in the RNA-sequencing libraries per genotype and background. P−/−, Prkra −/−; T−/−, Tarbp2 −/−; WT, wild-type.