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. 2018 Apr 5;18:392. doi: 10.1186/s12885-018-4308-7

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Flow diagram of Markov cohort model. Each pane represents a state of health. Straight lines with arrows indicate transition from one state to another one while circular arrows mean that some patients may stay at the same state for more than one cycle

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