Table 3.
Independent risk factors associated with long term death in patients admitted with severe infection
| Variable | Total | Dead at 5 years | Adjusted OR (95% CI) | |
|---|---|---|---|---|
| Model 1 | Model 2 | |||
| Age, mean ± SD, per year | 65 ± 20 | 74 ± 14 | 1,03 (1.02–1.04) |
1,04 (1.03–1.05) |
| Cancer, n (%) | 45 (4) | 36 (10) | 4.36 (1.65– 11.53) |
5.93 (2.26– 15.51) |
| Chronic haematologic disease, n (%) | 59 (6) | 35 (9) | 2.37 (1.14–4.93) |
|
| No comorbidities, n (%) | 352 (35) | 78 (21) | 0.40 (0.26–0.62) |
0.45 (0.29–0.69) |
| Karnofsky Index < 70, n (%) | 311 (31) | 195 (52) | 2.25 (1.48–3.40) |
2.32 (1.54–3.50) |
| Severity of infection, n (%) | ||||
| Infection | 275 (27) | 86 (23) | 1.00 | |
| Sepsis | 355 (35) | 125 (33) | 1.15 (0.72–1.83) |
|
| Severe sepsis | 292 (29) | 116 (31) | 1.33 (0.81– 2.17) |
|
| Septic shock | 91 (9) | 52 (14) | 3.77 (1.80– 7.89) |
|
| SAPS II, median ± SD, per point | 29 ± 13 | 35 ± 14 | 1.05 (1.03–1.07) |
|
| Positive blood cultures, n (%) | 151 (15) | 70 (19) | 1.57 (1.01–2.44) |
|
| Infection by an ESKAPE pathogen, n (%) | 113 (18) | 61 (24) | 1.61 (1.00–2.60) |
1.61 (1.00–2.60) |
OR Odds ratio, CI Confidence interval, ESKAPE Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter species