Fig. 7.

Prior synbiotic supplementation is associated with differences in bacterial taxa and inferred metabolic pathways during HFD challenge. a LEfSe generated cladogram of taxonomic differences of abundance. Areas shaded purple indicate bacterial taxa with a higher abundance in prior supplemented animals during HFD challenge, whereas areas shaded green indicate bacterial taxa with a higher abundance in untreated animals during HFD challenge. b LEfSe plot of inferred KEGG bacterial metabolic pathways. Bars to the left indicate inferred bacterial metabolic pathways enriched in untreated animals during HFD challenge, whereas bars to the right indicate inferred bacterial metabolic pathways enriched in prior supplemented animals during HFD challenge. Bar colors indicate higher-level metabolic pathways. c Plots of the relative abundance of differentially enriched carbohydrate metabolism pathways identified via LEfSe analysis of prior supplemented versus untreated animals during HFD challenge. Abbreviations used as in Fig. 4