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. 2018 Apr 5;18:122. doi: 10.1186/s12906-018-2189-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — mRNA expression levels of the regulation cholesterol activities associated genes ABCA1, SREBP2, CYP7A1, LXRα, AMPKα2 and HMGCR in HepG2 cells. All genes were normalized with GAPDH. HepG2 cells were treated with (1) SIM (10 μmol/L), (2) C + C + G + Q (1 μmol/L + 30 μmol/L + 10 μmol/L + 10 μmol/L) (3) CRO (1 μmol/L), (4) CGA (30 μmol/L), (5) GEN (10 μmol/L), (6) QUE (10 μmol/L) and no drug for (7) Control respectively for 48 h. Data represent as mean ± SEM of three independent experiments. ^*P < 0.05 vs. control, ^#P < 0.05 vs. SIM