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. 2018 Apr 5;19:47. doi: 10.1186/s13059-018-1426-0

Fig. 9.

Fig. 9

Snapshot of scRNA-seq profiling on progenitor cells and hPSCs. Differentiation trajectories of six progenitor cells derived from Primed H9 show key signaling pathways and TFs involved in the differentiation. The balance of lineage specifiers decides the reset result of Primed H9. MAPK-ERK1/2 signaling pathway related genes are enriched in Naïve-like H9, which may contribute to the hematopoietic differentiation bias