Table 2.

MMRM results for ADAS-cog13 at week 6 (visit 3) and week 12 (visit 5)

Visit	Treatment group	n	LS mean (SE)	80% CI	Difference (SE)	80% CI for difference	Two-sided P value
Week 6	SAM-760	84	−0.71 (0.50)	−1.36, −0.06	0.74 (0.70)	−0.16, 1.64	0.29
	Placebo	93	−1.45 (0.48)	−2.06, −0.83
Week 12	SAM-760	78	0.11 (0.63)	−0.70, 0.92	0.70 (0.87)	−0.42, 1.82	0.43
	Placebo	86	−0.58 (0.60)	−1.36, 0.19

ADAS-cog13 Alzheimer’s Disease Assessment Scale-cognitive subscale, CI confidence interval, LS least squares, MMRM mixed model repeated measures, SE standard error