Table 3.

Univariate Cox regression analysis for PTC recurrence in the training and testing patient sets

	Training set		Testing set
Factor	HR(95% CI)	p	HR(95% CI)	p
All patients	414		609
Age (years)		0.622		0.753
≤45	1 (reference)		1 (reference)
>45	0.982 (0.457 to 1.452)		0.872(0.562 to 1.654)
Age (years)		0.672		0.261
≤55	1 (reference)		1 (reference)
>55	1.524 (0.782 to 2.281)		1.622 (0.891 to 2.462)
Gender		0.321		0.271
Female	1 (reference)		1 (reference)
Male	1.451 (0.661 to 2.992)		1.652 (0.842 to 2.721)
Postoperative RAI		0.172		0.283
Yes	1 (reference)		1 (reference)
No	0.872 (0.521 to 1.726)		0.982 (0.475 to 2.228)
Race		0.372		0.208
Han	1 (reference)		1 (reference)
Other	1.211 (0.872 to 1.872)		1.253 (0.772 to 2.011)
BRAF mutation		0.382		0.229
Positive	1 (reference)		1 (reference)
Negative	0.871 (0.622 to 1.263)		0.982 (0.821 to 1.461)
T classification		0.021		0.008
T1-2	1 (reference)		1 (reference)
T3-4	3.261 (1.271 to 5.653)		3.876 (1.532 to 6.211)
PTC nodule number		0.152		0.102
Single	1 (reference)		1 (reference)
Multiple	1.933 (0.891 to 2.901)		2.011 (0.902 to 3.110)
N classification		0.048		0.041
N0	1 (reference)		1 (reference)
N1	1.502 (1.029 to 2.893)		1.462 (1.081 to 3.011)
M classification		<0.001		<0.001
M0	1 (reference)		1 (reference)
M1	8.662 (3.092 to 16.223)		9.920 (3.825 to 21.273)
Serum fibrinogen levels		0.012		0.007
Low	1 (reference)		1 (reference)
High	3.457 (2.203 to 6.782)		4.228(2.102 to 7.541)