Table 2.
Characteristic | Left Unilateral | Right Unilateral | P Value |
---|---|---|---|
Patients, n (%) | 894 (75.2) | 295 (24.8) | |
Mean age, y | 61.5 (12.87) | 60.1 (13.2) | 0.11 |
Sex, % | |||
Female | 70.1 | 61.0 | 0.004 |
Male | 29.9 | 39.0 | |
Race, % | |||
White | 72.2 | 68.8 | 0.24 |
Black | 8.1 | 6.4 | |
Hispanic | 5.2 | 7.5 | |
Other | 14.6 | 17.3 | |
Mean BMI, kg/m2a | 29.6 (6.70) | 31.0 (7.16) | <0.01 |
Creatinine, mg/dLb | 1.01 (0.83) | 0.96 (0.50) | 0.37 |
Smoking status, % | |||
Nonsmoker | 39.0 | 41.0 | 0.58 |
Current or past smoker | 61.0 | 59.0 | |
Comorbidity at baseline,c % | |||
Hypertension | 58.3 | 59.0 | 0.84 |
Prediabetes | 6.3 | 7.5 | 0.50 |
Type 2 diabetes | 20.8 | 22.0 | 0.68 |
Composite diabetes | 27.1 | 29.5 | 0.45 |
Hyperlipidemia | 51.0 | 49.2 | 0.59 |
Coronary artery disease | 15.4 | 15.6 | 0.93 |
Peripheral arterial disease | 9.1 | 5.4 | 0.0498 |
Myocardial infarction | 6.5 | 6.4 | 1.00 |
Stroke | 4.4 | 1.7 | 0.033 |
Atrial fibrillation | 7.6 | 6.8 | 0.70 |
Chronic kidney disease | 8.5 | 8.1 | 0.90 |
Composite cardiovascular diseased | 72.3 | 72.3 | 1.00 |
Medications at baseline,c % | |||
Hypertension | 55.5 | 53.9 | 0.64 |
Diabetes | 15.9 | 20.0 | 0.11 |
Hyperlipidemia | 40.7 | 38.6 | 0.54 |
Coronary heart disease | 34.2 | 32.5 | 0.62 |
Average follow-up time,e y (standard deviation) | 5.1 (4.26) | 5.5 (4.38) | 0.18 |
Eighty-three patients did not have BMI measured at the time of the baseline imaging.
Sixty-two patients did not have creatinine measured at the time of the baseline imaging.
Baseline defined as date of earliest radiologic imaging demonstrating adrenal adenoma.
Composite cardiovascular disease defined as diagnosis of hypertension, myocardial infarction, cardiovascular disease, stroke, or peripheral arterial disease.
Follow-up time defined as the period of time from earliest radiologic image demonstrating adrenal adenoma to the most recent comprehensive clinic visit.