Table 1.
Population baseline characteristics
| Total population | IHD | SHD | P | |
|---|---|---|---|---|
| n = 41 | n = 21 | n = 20 | (between IHD and SHD) | |
| General characteristics | ||||
| Age (years)a | 72 (17) | 68 (19) | 77 (10) | 0.02 |
| Age <65 yearsb | 13 (31.7%) | 9 (42.8%) | 4 (20%) | 0.16 |
| Age >75 yearsb | 15 (36.6%) | 4 (19%) | 11 (55%) | 0.02 |
| Menb | 20 (48.8%) | 9 (42.8%) | 11 (55%) | 0.54 |
| Renal parameters | ||||
| Creatinine at dialysis initiation (µmol/L)a | 598 (356) | 477 (375) | 723 (822) | 0.05 |
| AKI on chronic renal diseaseb | 6 (14.6%) | 2/19 (10.5%) | 4/19 (21%) | 0.66 |
| Renal biopsyb | 13 (31.7%) | 9 (42.8%) | 4 (20%) | 0.18 |
| Proteinuria (g/24 h)a | 2.98 (2.6) | 2.7 (1.5) | 3.7 (3) | 0.10 |
| Proteinuria ≥2 g/24 hb | 30/38 (78.9%) | 16/21 (76.1%) | 14/17 (82.3%) | 0.70 |
| MM characteristics | ||||
| sFLC (mg/L)a | 6870 (10740) | 5475 (10396) | 9680 (16276) | 0.19 |
| M protein by ELP (g/L)a | 19.3 (37.8) | 36 (41) | 17 (14) | 0.26 |
| Monoclonal plasma cells in bone marrowa | 27.5% (37) | 30% | 25% | 0.87 |
| MM IgGb | 18 (43.9%) | 8 (38%) | 10 (50%) | 0.54 |
| MM LCb | 17 (41.5%) | 8 (38.1%) | 9 (45%) | 0.76 |
| De novo MMb | 29 (70.7%) | 15 (71.4%) | 14 (70%) | 1.00 |
| Kappa sFLCsb | 20 (48.8%) | 9 (42.8%) | 11 (55%) | 0.54 |
| Plasma cell leukaemiab | 3 (7.3%) | 0 | 3 (15%) | 0.10 |
| Main complications | ||||
| Anaemia (haemoglobin level, g/dL)a | 8.75 (2.15) | 8.45 (2.6) | 9.1 (2) | 0.18 |
| Lytic bone lesionsb | 30/40 (75%) | 15/20 (75%) | 15 (75%) | 1.00 |
| Hypercalcaemia (> 3 mmol/L)b | 5/40 (12.5%) | 3/20 (15%) | 2 (10%) | 1.00 |
| Identified AKI precipitating factorb | 26 (63.4%) | 13 (61.9%) | 13 (65%) | 1.00 |
a
Median and IQR.
b
Number and (percentage).
ELP, electrophoresis; LC, light chains.