Table 3.
Effect of sub-acute exposure to Cr(VI) in kidney on different enzyme activities
| Metabolic enzymes | Kidney tissue |
|
|---|---|---|
| Control | Treated | |
| PDH (unit/min/mg of protein) (6) | 1.88 ± 0.10 | 1.12 ± 0.08; P < 0.001 |
| Alkaline phosphatase (King–Armstrong unit/mg of tissue) (6) | 0.64 ± 0.04 | 1.29 ± 0.08; P < 0.001 |
| NADH dehydrogenase (mmol of NADH oxidized/min/mg of protein) (6) | 6.78 ± 0.62 | 1.7 ± 0.39; P < 0.001 |
| Pronase activity (nmol of tyrosine/min/mg of protein) (6) | 1.38 ± 0.4 | 0.28 ± 0.09; P < 0.001 |
| Cathepsin activity (nmol of tyrosine/min/mg of protein) (6) | 1.03 ± 0.06 | 0.33 ± 0.07; P < 0.001 |
| Trypsin activity (nmol of tyrosine/min/mg of protein) (6) | 35.08 ± 3.2 | 13.04 ± 3.33; P < 0.001 |
Values are means ± SEM. Figures in parentheses indicate number of animals. P < 0.05 and P < 0.001 are considered statistically significant.