Table 2.
Mean (SD) biomarker levels for the patient groups in the primary analysis
| Biomarker | Mean (SD) in women with no VTE N = 247 | Mean (SD) in women with VTE N = 36 | P‐value |
|---|---|---|---|
| APTT | 39.7 (22.07) | 41.4 (13.24) | 0.660 |
| Clauss fibrinogen | 5.37 (1.69) | 6.30 (2.73) | 0.007 |
| C‐reactive protein | 5348 (1705) | 5603 (1646) | 0.401 |
| Prothombin time | 16.2 (5.39) | 18.7 (13.16) | 0.089 |
| D‐Dimer (ELISA) | 1247 (1474) | 2401 (2642) | 0.001 |
| D‐Dimer (Innovance) | 1.147 (1.269) | 2.282 (3.388) | 0.004 |
| Thrombin Generation (Lag Time) | 8.70 (4.84) | 13.85 (8.30) | <0.001 |
| Thrombin Generation (Endogenous Potential) | 1217 (558) | 1081 (561) | 0.241 |
| Thrombin Generation (Time to Peak) | 14.8 (9.06) | 21.5 (13.61) | 0.001 |
| Thrombin Generation (Peak) | 162 (116) | 130 (124) | 0.160 |
| Plasmin –antiplasmin complexes | 688 (251) | 915 (647) | 0.004 |
| BNP | 372 (900) | 385 (731) | 0.932 |
| MRproANP | 603 (1016) | 753 (1159) | 0.415 |
| Soluble Tissue Factor | 291 (319.6) | 488 (1067.3) | 0.065 |
| Prothrombin fragment 1 + 2 | 623 (408) | 550 (333) | 0.298 |
| Troponin | 1.328 (2.458) | 0.762 (0.968) | 0.105 |
APTT, activated partial thromboplastin time; BNP, brain natriuretic peptide; ELISA, enzyme‐linked immunosorbent assay; MRproANP; mid‐regional pro‐atrial natriuretic peptide; SD, standard deviation; VTE, venous thromboembolism.