Table 4.
Mean (SD) biomarker levels for the patient groups with those having received anticoagulation excluded
| Biomarker | Mean (SD) in women with no VTE N = 62 | Mean (SD) in women with VTE N = 4 | P‐value |
|---|---|---|---|
| APTT | 33·4 (16·67) | 33·4 (6·57) | 0·993 |
| Prothombin time | 14·8 (2·108) | 14·2 (0·772) | 0·610 |
| Clauss fibrinogen | 5·41 (1·81) | 6·61 (2·61) | 0·219 |
| D‐Dimer (ELISA) | 1114 (848) | 832 (667) | 0·517 |
| D‐Dimer (Innovance) | 1·126 (0·826) | 0·797 (0·420) | 0·432 |
| Thrombin Generation (Lag Time) | 6·20 (1·646) | 6·98 (0·919) | 0·354 |
| Thrombin Generation (Endogenous Potential) | 1501 (389) | 1575 (351) | 0·711 |
| Thrombin Generation (Time to Peak) | 10·03 (2·57) | 10·31 (1·40) | 0·823 |
| Thrombin Generation (Peak) | 235 (100·3) | 248 (71·0) | 0·798 |
| Plasmin –antiplasmin complexes | 678 (205) | 821 (276) | 0·204 |
| BNP | 256 (586·31) | 29 (5·47) | 0·205 |
| MRproANP | 478 (904) | 1371 (1358) | 0·095 |
| Soluble Tissue Factor | 222 (157·8) | 164 (37·4) | 0·428 |
| Prothrombin fragment 1 + 2 | 711 (386) | 373 (161) | 0·095 |
| Troponin | 1·03 (1·24) | 2·12 (1·65) | 0·122 |
| C‐reactive protein | 5410 (1596) | 5884 (1734) | 0·564 |
APTT, activated partial thromboplastin time; BNP, brain natriuretic peptide; ELISA, enzyme‐linked immunosorbent assay; MRproANP; mid‐regional pro‐atrial natriuretic peptide; SD, standard deviation; VTE, venous thromboembolism.