Figure 1.

Study design. Patients who had achieved at least a 50% improvement in PASI 50 from baseline at week 12 were re‐randomized during treatment period 2 to either continue the same treatment on a once‐weekly dosing schedule, or to undergo a sequence of 3 treatment switches between GP2015 and ETN at 6‐week intervals until week 30. Of the 14 patients who did not enter treatment period 2, 5 patients did not achieve PASI 50 at week 12 (3 others who also did not achieve PASI 50 continued erroneously during treatment period 2); 7 patients discontinued immediately after week 12 (3 patients were not re‐randomized; 4 were re‐randomized but did not take any study drug during treatment period 2); 2 patients achieved PASI 50 at week 12 but had no data beyond week 12. ETN=etanercept originator product