TABLE II. Cryptococcosis in Latin America. Clinical presentation and treatment.
| Country | Number of cases | Percentage of cases | Reference | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Clinical presentation (%) | AmB | AmB + FCZ | AmB + 5FC | AmB + FCZ or 5FC | FCZ | Other | |||
| Argentina | |||||||||
| Buenos Aires | 2041 | Meningitis (90) | 100 (1996-2009) | 100 from 2010 | 100 (1986-1995) | Arechavala et al. (2017) | |||
| Provincia de Buenos Aires | 106 | Neuro (91) | 100 | Mónaco and Antabak (2008) | |||||
| Brazil | |||||||||
| Bahia (Salvador) | 50 | Meningitis (100) | 62 | 32 | 0 | 4 | 2 | Mascarenhas-Batista et al. (2013) | |
| Mato Grosso do Sul (Campo Grande) | 123 | Neuro (84) | 86 | 60a | Lindenberg et al. (2008) | ||||
| Mina Gerais (Uberlandia) | 96 | Meningitis (56) | 54 | 19 | 0 | 3 | 3 | Moreira et al. (2006) | |
| Mina Gerais (Uberlandia) | 41 | Meningitis (75) | 85 | 75a | Aguiar et al. (2017) | ||||
| São Paulo (São Paulo) | 29 | Neuro (86) | 100 including LAmB | 3 | Lomes et al. (2016) | ||||
| National, children | 32 | 28 | 66 | ||||||
| Bolivia | |||||||||
| Cochabamba | 31 | Meningitis (100) | 100 | Castro and Córdoba (2014) | |||||
| Colombia | |||||||||
| National 1997-2005 | 931 | Neuro (96) | 73 | 21 | 6 | Lizarazo et al. (2007) | |||
| National 2006-2010 | 526 | Neuro (81) | 72 | 28 | Escandón et al. (2012) | ||||
| Norte de Santander (Cúcuta) | 90 | Meningitis (100) | 93 | Lizarazo et al. (2012) | |||||
| Atlántico | 41 | Meningitis (66) | 29 | 5 | 17 | Noguera et al. (2015) | |||
| National, children | 41 | Meningitis (88) | 61 | 16 | 6 | 3 | 3 | 9 | Lizarazo et al. (2014a) |
| Costa Rica | |||||||||
| San José | 71 | Cerebral (73) | 79 | 21 | Ávila and Villalobos (2016) | ||||
| Cuba | |||||||||
| La Habana | 16 | Neuro (100) | 69 | 23 | 8 | Fernández-Concepción et al. (2003) | |||
| Guatemala | |||||||||
| Guatemala | 110 | Meningitis (100) | 78 (15) * | 6 | Romero et al. (2005) | ||||
| Panamá | |||||||||
| Panamá | 28 | Meningitis (100) | 100 | González et al. (2013) | |||||
| Paraguay | |||||||||
| Itauguá | 13 | Meningitis (100) | 85 | 7 | Sierra (2013) | ||||
| Peru | |||||||||
| Lima | 47 | Meningitis (100) | 100 | Dammert et al. (2008) | |||||
| Lima | 234 | Meningitis (100) | 62 | 25 | 13 | Concha-Velasco et al. (2017) | |||
a: consolidation phase; AmB: amphotericin B; *LAmB: liposomal amphotericin B; FCZ: fluconazole; 5FC: 5 fluocytosine; neuro: meningitis, meningoencephalitis and cryptococcoma.