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. 2017 Dec 22;21(4):371–381. doi: 10.1093/ijnp/pyx116

Figure 1.

Figure 1.

Effect of a serotonin (5-HT)1A receptor antagonist on the acute antidepressant effects of ketamine. The drug administration schedules are illustrated in A, D, and G. Vehicle A, saline; vehicle B, Ringer’s solution. Values indicate the mean±SEM. (B), n=6–7; (C), n=8; (E), n=8; (F), n=6; (H), n=7–9; (I), n=6. *P<.05, **P<.01 compared with vehicle A-treated vehicle A (B), vehicle B-treated vehicle A (E), and vehicle A (H), ##P<.01 compared with vehicle A-treated ketamine (B), vehicle B-treated ketamine (E).