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Mre11-R522H and Mre11-N631Y do not suppress the resection defect of sae2Δ cells. (A, B) DSB resection. YEPR exponentially growing cell cultures were transferred to YEPRG at time zero. SspI-digested genomic DNA separated on alkaline agarose gel was treated as in Figure 2. (C) Densitometric analysis. The experiment as in (A, B) was independently repeated and the mean values are represented with error bars denoting S.D. (n = 3).
