Table 1.
Response to Individual Items of CAST at Baseline in CO-MED Trial Participants (n = 664)
| Domain of CAST | Strongly Disagree | Disagree | Neither Agree nor Disagree | Agree | Strongly Agree | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No.# | Individual Items | N | % | N | % | N | % | N | % | N | % | Mean | SD | |
| 1 | I feel anxious all the time | Anxiety | 55 | 8.3 | 148 | 22.3 | 121 | 18.2 | 221 | 33.3 | 119 | 17.9 | 3.30 | 1.23 |
| 2 | I have been feeling really good lately | Mania | 308 | 46.4 | 270 | 40.7 | 48 | 7.2 | 27 | 4.1 | 11 | 1.7 | 1.74 | 0.88 |
| 3 | I feel as if I am going to have a heart attack | Panic | 304 | 45.8 | 171 | 25.8 | 90 | 13.6 | 74 | 11.1 | 25 | 3.8 | 2.01 | 1.17 |
| 4 | I wish people would just leave me alone | Irritability | 54 | 8.1 | 91 | 13.7 | 153 | 23.0 | 239 | 36.0 | 127 | 19.1 | 3.44 | 1.18 |
| 5 | I have been having more trouble sleeping than usual | Insomnia | 50 | 7.5 | 108 | 16.3 | 77 | 11.6 | 226 | 34.0 | 203 | 30.6 | 3.64 | 1.27 |
| 6 | I am feeling restless, as if I have to move constantly | Anxiety | 84 | 12.6 | 150 | 22.6 | 124 | 18.7 | 233 | 35.1 | 73 | 11.0 | 3.09 | 1.23 |
| 7 | I suddenly feel very confident | Mania | 308 | 46.4 | 250 | 37.6 | 66 | 9.9 | 32 | 4.8 | 8 | 1.2 | 1.77 | 0.90 |
| 8 | I am more talkative than normal | Mania | 247 | 37.2 | 271 | 40.8 | 88 | 13.2 | 51 | 7.7 | 7 | 1.1 | 1.95 | 0.95 |
| 9 | I feel very uptight | Irritability | 56 | 8.4 | 102 | 15.4 | 110 | 16.6 | 285 | 42.9 | 111 | 16.7 | 3.44 | 1.18 |
| 10 | I find myself saying or doing things without thinking | Irritability | 86 | 13.0 | 202 | 30.4 | 120 | 18.1 | 205 | 30.9 | 51 | 7.7 | 2.90 | 1.20 |
| 12 | I can feel my heart racing | Panic | 159 | 24.0 | 193 | 29.1 | 95 | 14.3 | 170 | 25.6 | 47 | 7.1 | 2.63 | 1.29 |
| 13 | Lately everything seems to be annoying me | Irritability | 17 | 2.6 | 87 | 13.1 | 111 | 16.7 | 295 | 44.4 | 154 | 23.2 | 3.73 | 1.04 |
| 14 | I slept very little last night | Insomnia | 65 | 9.8 | 147 | 22.1 | 65 | 9.8 | 216 | 32.5 | 171 | 25.8 | 3.42 | 1.34 |
| 15 | I cannot sit still | Anxiety | 104 | 15.7 | 185 | 27.9 | 129 | 19.4 | 199 | 30.0 | 47 | 7.1 | 2.85 | 1.21 |
| 16 | I find people get on my nerves easily | Irritability | 21 | 3.2 | 65 | 9.8 | 91 | 13.7 | 317 | 47.7 | 170 | 25.6 | 3.83 | 1.02 |
| 17 | I have been having lots of great ideas | Mania | 218 | 32.8 | 249 | 37.5 | 99 | 14.9 | 69 | 10.4 | 29 | 4.4 | 2.16 | 1.12 |
CO-MED, Combining Medications to Enhance Depression Outcomes.
No. refers to the item numbers originally reported in the 17-item CAST as reported in Figure 1 of Trivedi et al. primary CAST paper (Trivedi et al., 2011). Note that 16-item CAST SR excluded item 11 as it loaded on 2 different factors.