Table 2.

Multiply imputed unadjusted mean costs (€, 2014) at 8 weeks, 6 months, and 12 months follow‐up

Outcome	Intervention Group	Control Group	Mean Difference (95% CI)
8 weeks (n = 763)
Clinical effects
Improvement in CES‐D	9.8	8.3	1.5 (− .4 to 3.4)
Response rate	.22	.19	.04 (− .02 to .10)
QALY	.10	.10	0 (− .01 to .01)
Cost categories
Intervention	268	0	268 (N/A)
Mental health	152	143	9 (− 33 to 52)
Primary care	76	73	3 (− 19 to 24)
Secondary care	108	120	−12 (− 82 to 56)
Medication	1	2	−1 (− .5 to 1.5)
Complementary therapy	11	10	1 (− 5 to 8)
Domestic help	391	380	11 (− 103 to 123)
Productivity losses	1,061	1,058	3 (− 305 to 309)
Total	2,068	1,786	282 (− 98 to 659)
6 months (n = 1,163)
Clinical effects
Improvement in CES‐D	9.24	7	2.24 (.8–3.7)
Response rate	.20	.18	.02 (− .02 to .07)
QALY	.36	.35	.01 (− .01 to .02)
Cost categories
Intervention	243	5	238 (233–242)
Mental health	268	234	34 (− 115 to 46)
Primary care	164	129	35 (0–70)
Secondary care	482	334	148 (− 187 to 485)
Medication	5	5	0 (− 2 to 2)
Complementary therapy	18	22	−4 (− 15 to 6)
Domestic help	907	750	157 (− 65 to 379)
Productivity losses	2,350	2,580	−230 (− 758 to 161)
Total	4,437	4,059	378 (− 343 to 1,040)
12 months (n = 906)
Clinical effects
Improvement in CES‐D	11.7	9.6	2.1 (.1–4)
Response rate	.27	.24	.3 (− .03 to .08)
QALY	.76	.76	.00 (− .3 to .3)
Cost categories
Intervention	238	4	234 (230–239)
Mental health	563	646	−83 (− 272 to 134)
Primary care	270	239	31 (− 47 to 103)
Secondary care	731	429	302 (− 154 to 741)
Medication	10	11	−1 (− 6 to 5)
Complementary therapy	42	51	−9 (− 35 to 18)
Domestic help	2,059	1,712	347 (− 168 to 802)
Productivity losses	4,335	4,652	−317 (− 1,182 to 692)
Total	8,248	7,744	504 (− 1,149 to 1,892)