Figure 3.

Relative risk of death by HbA1c decile when HbA1c is modelled as a mean, quarterly updated, time‐dependent covariate. Data from alternative models are detailed in Figure S3. A, Metformin monotherapy. B, Regimens with a low hypoglycaemia risk. C, Sulphonylurea monotherapy. D, Insulin monotherapy. E, Regimens with a higher hypoglycaemia risk excluding insulin. F, Regimens with a higher hypoglycaemia risk including insulin. Vertical error bars represent the 95% confidence interval (CI) for adjusted hazard ratio (aHR) and the horizontal error bars represent the glycated haemoglobin (HbA1c) range