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. 2018 Mar 6;39(2):79–132. doi: 10.1210/er.2017-00253

Table 1.

Long-Term Studies or Preventive Interventions in Children and Adolescents

Reference Sample Design Results
Epstein et al., 2001 (102) 26 children 12-mo RCT 1.1% decrease in overweight prevalence with increased fruits and vegetables vs 2.4% with decreased fat and sugar
6–11 y old Increased fruits and vegetables vs decreased fat and sugar Differences not significant
James et al., 2004 (103) 644 children 1-y intervention; classrooms randomized to reduce sugar drink consumption No significant difference in BMI z-score
7–11 y old
Ebbeling et al., 2012 (104) 224 overweight or obese adolescents; mean age 15 y RCT Significantly lower rates of weight gain in intervention group
Sugar-free drinks and behavior modification vs untreated control
de Ruyter et al., 2012 (105) 641 children 18-mo RCT Significantly lower rates of weight gain among group receiving sugar-free drinks
5–12 y old Sugar-free drinks vs drinks containing sugar at lunch
Sallis et al., 2009 (106) 995 4th and 5th grade students PE taught by PE instructor or teacher vs control Some fitness measures improved in girls
No significant differences in changes in skinfolds
Caballero et al., 2003 (107) 1704 Native American children 8–11 y old 3-y study randomized by schools to control or intervention (41 schools); No significant difference in body composition or PA
changes in dietary intake, increased PA, classroom curriculum changes, family involvement
Gortmaker et al., 1999 (108) 1295 6th–7th grade students 2-y RCT with five intervention and five control schools Decreased prevalence of obesity in girls
Decreased TV, decreased fat and increased fruit and vegetable intakes, and PA
Plachta-Danielzek et al., 2011 (109) 240 intervention and 952 nonintervention children Nutrition intervention delivered within schools and daily running games vs controls No significant difference in increases in overweight between intervention and control students in 8-y follow-up
Mean age 6 y old Significant decreases in BMI z-scores with upper income students
Sahota et al., 2001 (110) 636 children, 7–11 y old Randomized by school. Teacher training, changes in school meals, and development of school actions plans to promote healthy eating and PA No significant differences in BMI in intervention compared with control schools
314 intervention
322 control

Abbreviations: PA, physical activity; PE, physical education; RCT, randomized controlled trial; TV, television.