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. 2018 Jan 9;11(2):179–190. doi: 10.1093/ckj/sfx143

Fig. 3.

Fig. 3.

Focal global glomerulosclerosis; 32 year old Caucasian man with nephrotic-range proteinuria (7 g/day), normal serum albumin (4 g/dL) and normal renal function (creatinine clearance 90 mL/min). Genetic tests revealed heterozygous mutation R213H on exon 4 of the INF2 gene (see Table 3, patient 5). (A, B) Light microscopy showing mild focal global glomerulosclerosis (silver methenamine A, ×20, B, ×40). (C, D) EM showing segmental foot process effacement; black arrow points to segmental foot process effacement (C, ×3500 and D, ×6000).