Table 4.

Multiple logistic regression model for faster CKD progression

Variable	Odds ratio	95% CI odds ratio	P
Age, years	0.980	0.970; 0.990	<0.0001
Sex, male = 1	1.401	1.045; 1.879	0.024
Systolic blood pressure, ×10 mmHg	1.081	1.021; 1.144	0.008
Proteinuria, g/g creatinine	1.413	1.301; 1.534	<0.0001
Treatment with dual RAS blockade (0, 1)	2.163	1.268; 3.689	0.005
MTMa (0, 1)	0.445	0.259; 0.764	0.003

Not in equation: study periods, smoking, diastolic blood pressure, baseline eGFR, diabetes, comorbidity index, diuretics, ACEI or ARB therapy, β-blockers, calcium-channel blockers, antiplatelet drugs, statins.

^aMTM: discontinuation at baseline of vitamin D analogues, fibrates and/or allopurinol (only in patients with suspected allopurinol hypersensitivity).