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Liver injury score (A), liver MPO activity (B), plasma ALT levels (C), plasma AST levels (D), and liver ATP content (E) in young AMPKα1 WT and KO mice subjected to CLP. Data represent means ± sem (n = 5–9 mice for each group). *P < 0.05 vs. sham-treated mice; ‡P < 0.05 vs. WT mice. Survival rate of young AMPKα1 WT and KO mice subjected to CLP. Curves represent rate of 15 mice for each group. *P < 0.05 vs. vehicle-treated mice by χ2 test.
