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Activation of OGR1 by various benzodiazepines, as assessed in a yeast-based screen. Dose-dependent effect of the benzodiazepines lorazepam, DMD, clobazam, diazepam, and sulazepam on yeast growth in the strain MPY578q5 overexpressing OGR1/GPR68. Data are expressed as the percentage of the lorazepam response at 1 µM. OD, optical density.
