Fig. 3.

—Editing events occur in close proximity to each other. This figure shows the significant propensity of edits to occur in the same, or adjacent, codon as other edits. For each codon position, the number of edits expected to occur in the same or adjacent codon was determined based on a random distribution of edits with the same codon position preferences as observed in real data. Comparison of the actual distribution to the expected distribution showed highly significant clustering when considering edits in all three positions. Error bars represent SD of the simulation (n=100).