Table 1. Markers used for cell type inference from the PBMC data.
| Cluster ID | Potential cell type | Markers |
|---|---|---|
| 1 | Naive T cells | CD27 (22), CCR7 (23), CD8A, CD8Ba |
| 2 | CD4+ memory cells | IL7R (24), CD27 (22), CCR7 (23) |
| 3 | NKT cells | ZNF683 (25,26) (UniProtKB - Q8IZ20), CD8A, CD8Ba |
| 4 | B cells | CD79A (27), CD37 (28) |
| 5 & 7 | CD8+ T cells | GZMK (29), CD8A, CD8Ba |
| 6 | NK cells | CD160 (30,31), NKG7 (32), GNLY (33), CD247 (34), CCL3 (35), GZMB (36) |
| 8 & 9 | CD16+ and CD14+ monocytes | CD68 (37), CD16 (FCGR3A) (38), CD14 (38), S100A12 (39,40) |
| 10 | Regulatory T cells | CCR10, CD25(IL2RA)a, CD52 (41), CMTM7, FOXP3 (42)a |
| 11 | Monocyte derived dendritic cells | CST3 (43), CD1C (44,45), FCER1A (43) |
| 12 | Megakaryocyte progenitors | PF4 (46),PPBP (47), PLA2G12A (48) |
| 13 | Progenitor-NK cells | ID2 (49,50) |
| 14 | Plasmacytoid dendritic cells | GZMB (51), CD123 (IL3RA) (52) |
aMarkers that are well-known but failed to qualify the gene selection criteria.