Transmission electron micrograph of bacteria reveals: (A) OMVs released by Gram-negative bacteria, Serratia marcescens UG-159 (arrows) (This image is adapted from Ref22, Li Z, et al. J Bacteriol 1998); (B) MVs released by Gram-positive bacteria S. aureus (arrows) (This image is adapted from Ref79, Lee EY, et al. Proteomics, 2009).