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. 2018 Mar 6;5(4):ofy050. doi: 10.1093/ofid/ofy050

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© The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 1. — Kinetics of torque teno virus (TTV)– and Epstein-Barr virus (EBV)–DNA levels, in serum and whole blood respectively, before and during the follow-up period after lung transplantation. TTV-DNA levels in serum starting pre–lung transplantation (LTx) were determined by real-time polymerase chain reaction (PCR). Individual TTV levels are indicated by dots. EBV-DNA levels in whole blood post-LTx were determined by real-time PCR, and individual EBV levels are indicated by dots. Patients receiving either Tacrolimus treatment (n = 19) or Cyclosporine treatment (n = 79) are indicated by red and blue dots, respectively. The mean levels of TTV and EBV in Tacrolimus-treated patients are indicated by red lines in their respective graphs. The mean levels of TTV and EBV in Cyclosporine-treated patients are indicated by blue lines in their respective graphs. Infectious events and acute rejections are indicated by black dots. Statistical calculations were done using Mann-Whitney U (P values are indicated by ^*<.05, ^**<.01, and ^***<.001). ⁺⁺The levels of EBV-DNA pre-LTx were determined in serum samples. Abbreviations: CMV, cytomegalovirus, reject: acute rejection of which all but 3 were biopsy-verified; LOQ, level of quantification; viral RI, viral respiratory tract infection.