Figure 4.

Early upregulation of myocardial CTGF and TGF-β transcript levels appeared as early as six hours after Ang-II exposure. Myocardial (a) CTGF and (b) TGF-β transcript levels after six or 24 hours of Ang-II infusion relative to saline controls. Transcript levels are reported relative to housekeeping gene ribosomal 18S.

Data are expressed as means ± SEM.

n = 5–6.

*p < 0.05, **p ≤ 0.01 and ***p ≤ 0.001, compared to saline controls.

Ang-II: Angiotensin II; CTGF: connective tissue growth factor; TGF-β: transforming growth factor-β.