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Observed proportion of significant associations at different α levels. We conducted association tests for ovarian (A–C) and breast (D–F) cancer, using eight association tests supported in XPAT. We calculated the proportions of significant associations at α levels of 0.001, 0.01 and 0.05 (dashed lines in each sub panel), and compared the performance of XPAT’s QC metrics versus benchmark QC metrics for each method and dataset.
