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. 2017 Dec 23;46(6):e32. doi: 10.1093/nar/gkx1280

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — Power estimation for association tests using XPAT. The lines depict the power comparisons with VAAST 2 analysis with XPAT using TCGA ovarian cancer cases and NDAR controls (solid lines) and using platform-matched ovarian cancer cases and controls (dashed lines), for four genes: BRCA1 (red), BRCA2 (orange), RAD51D (blue), RAD51C (green). The x-axis shows the α level and the y-axis shows the statistical power. The power was calculated based on 1000 bootstraps. For each bootstrap, we sampled 250 cases and 1000 controls with replacement from each dataset.