Table 1.

Characteristics of Diagnostic Cases

Characteristic	Value
No. of specimens	204
No. of individual FISH tests (probes or probe sets)	791
Patient age, median (range), y	63 (19-85)
No. of men/women (ratio)	124/80 (1.5)
Diagnosis, No. (%)
AML RCA	37 (18.1)a
AML NOS	88 (43.1)
AML MRC	67 (32.8)
tAML	11 (5.4)
MPAL	1 (0.5)

AML MRC, acute myeloid leukemia with myelodysplasia-related changes; AML NOS, acute myeloid leukemia not otherwise specified; AML RCA, acute myeloid leukemia with recurrent cytogenetic abnormalities; FISH, fluorescence in situ hybridization; MPAL, mixed-phenotype acute leukemia; tAML, therapy-related acute myeloid leukemia.

^aCytogenetic findings in AML RCA cases: t(8;21) in three (1%), inv(16) in 12 (6%), t(15;17) in 14 (7%), KMT2A in five (2.5%), t(6;9) in one (0.5%), inv(3) in two (1%).