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. 2017 Dec 20;162(2):611–621. doi: 10.1093/toxsci/kfx283

Figure 6.

Figure 6.

The brain levels of cytokines in rats 24 h after DFP and AEOL10150 treatment. The level of (A) TNF-α, (B) IL-β, (C) IL-6, or (D) KC/GRO in the hippocampus and piriform cortex of rats 24 h after DFP with standard therapy alone or with AEOL10150. Midazolam 2 mg/kg i.m. and AEOL10150 7 mg/kg, s.c. treated 5 min after SE initiation and AEOL10150 5 mg/kg s.c. or saline every 4 h thereafter. Bars represent mean + SEM, *p < .01 versus saline + standard therapy, #p < .05 versus DFP + standard therapy + saline, 1-way ANOVA within given brain region, n = 5–7 per group.