Figure 1.
Effects of HU on the relative expression of Trp53, Trp63, and Trp73 in embryos. A–C, Relative expression levels of Trp53, Trp63, and Trp73. Each bar represents the fold change of the mean quantity of the transcript relative to Hprt. C, control; HU, hydroxyurea. P < .05, 2-way ANOVA followed by a Bonferroni post hoc test, n = 3. (*) denotes significant change compared with control group with the same genotype, (a) denotes significant change compared with the Trp53+/+ control group, and (b) denotes significant change compared with the Trp53+/+ HU-treated group.