Skip to main content
. 2017 Dec 20;162(2):499–508. doi: 10.1093/toxsci/kfx284

Figure 2.

Figure 2.

A, Dot plot of daily dose (mg) and FDA hepatic liability (n = 163/181) (106 drugs BSEP Noninhibitors, 21 BSEP Weak Inhibitors, and 36 BSEP Inhibitors). B, Summary of drugs given at ≥ 50 mg (Not Safe) and <50 mg (Safe) for Pedersen et al. (2013) dataset (n = 163/181) (106 drugs BSEP Noninhibitors, 21 BSEP Weak Inhibitors, and 36 BSEP Inhibitors). C, Summary of drugs given at ≥ 50 mg (Not Safe) and <50 mg (Safe) for Aleo et al. (2017) dataset (n = 125) (91 drugs BSEP Noninhibitors, 10 BSEP Weak Inhibitors, and 24 BSEP Inhibitors).