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. 2017 Dec 20;162(2):499–508. doi: 10.1093/toxsci/kfx284

Table 1.

Comparison of BSEP and Mitochondrial Toxicity Assays Associated With DILI (Aleo et al., 2014; Dataset)

Criteria % of Drugs With DILI Predicted Correctly, PPV % of DILI Missing in the Prediction, FNR % of DILI Predicted Accurately, ACC (n = 42)
BSEP 72.7% 0.0% 78.6%
Mitotox 94.1% 33.3% 78.6%
BDDCS class 2 80.0% 16.7% 78.6%