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. 2017 Dec 20;162(2):499–508. doi: 10.1093/toxsci/kfx284

Table 2.

Comparison of BSEP and Mitochondrial Toxicity Assays Associated With DILI (Schadt et al., 2015; Dataset)

Criteria % Correct (PPV) % DILI Missing (FNR) % ACC (True Positive + True Negative/106)
BSEP 69.2% 62.5% 65.5%
Mitotox 71.4% 79.2% 61.8%
Cellular toxicity 48.3% 70.8% 55.5%
BDDCS class 2 64.6% 35.4% 69.1%